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Feb 11, 2013

What is helix loop helix?

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    Feb 11, 2013

    A basic helix-loop-helix (bHLH) is a protein structural motif that characterizes a family of transcription factors. It should not be confused with the helix-turn-helix domain. bHLH transcription factors are often important in development or cell activity. BMAL1-Clock is a core transcription complex in the molecular circadian clock. Other genes, like c-Myc and HIF-1, have been linked to cancer due to their effects on cell growth and metabolism.

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