What does it mean when you dream that you are a nobody in life because you never picked a college major?
Means you need to fix things
It most likely means that you are stressing out about college. Chill! Don't put too much stress on yourself. Just slowly and calmly think things through. I'm sure you'll find your answer.
Dreams are just random synapses firing off in your brain. It means that picking a college major has been on your mind recently. Or you gave it a passing thought, once, ten years ago. Or someone you read about in a novel was picking a college major. Etc.